diff --git a/src/Spout/Common/Helper/GlobalFunctionsHelper.php b/src/Spout/Common/Helper/GlobalFunctionsHelper.php
index 8243bcc..3dcddaf 100644
--- a/src/Spout/Common/Helper/GlobalFunctionsHelper.php
+++ b/src/Spout/Common/Helper/GlobalFunctionsHelper.php
@@ -280,6 +280,17 @@ class GlobalFunctionsHelper
         return mb_convert_encoding($string, $targetEncoding, $sourceEncoding);
     }
 
+    /**
+     * Wrapper around global function stream_get_wrappers()
+     * @see stream_get_wrappers()
+     *
+     * @return array
+     */
+    public function stream_get_wrappers()
+    {
+        return stream_get_wrappers();
+    }
+
     /**
      * Wrapper around global function stream_get_line()
      * @see stream_get_line()
diff --git a/src/Spout/Reader/AbstractReader.php b/src/Spout/Reader/AbstractReader.php
index ee6af08..d6d38e2 100644
--- a/src/Spout/Reader/AbstractReader.php
+++ b/src/Spout/Reader/AbstractReader.php
@@ -19,6 +19,13 @@ abstract class AbstractReader implements ReaderInterface
     /** @var \Box\Spout\Common\Helper\GlobalFunctionsHelper Helper to work with global functions */
     protected $globalFunctionsHelper;
 
+    /**
+     * Returns whether stream wrappers are supported
+     *
+     * @return bool
+     */
+    abstract protected function doesSupportStreamWrapper();
+
     /**
      * Opens the file at the given file path to make it ready to be read
      *
@@ -62,6 +69,10 @@ abstract class AbstractReader implements ReaderInterface
      */
     public function open($filePath)
     {
+        if ($this->isStreamWrapper($filePath) && (!$this->doesSupportStreamWrapper() || !$this->isSupportedStreamWrapper($filePath))) {
+            throw new IOException("Could not open $filePath for reading! Stream wrapper used is not supported for this type of file.");
+        }
+
         if (!$this->isPhpStream($filePath)) {
             // we skip the checks if the provided file path points to a PHP stream
             if (!$this->globalFunctionsHelper->file_exists($filePath)) {
@@ -72,8 +83,7 @@ abstract class AbstractReader implements ReaderInterface
         }
 
         try {
-            // Need to use realpath to fix "Can't open file" on some Windows setup
-            $fileRealPath = realpath($filePath);
+            $fileRealPath = $this->getFileRealPath($filePath);
             $this->openReader($fileRealPath);
             $this->isStreamOpened = true;
         } catch (\Exception $exception) {
@@ -81,6 +91,67 @@ abstract class AbstractReader implements ReaderInterface
         }
     }
 
+    /**
+     * Returns the real path of the given path.
+     * If the given path is a valid stream wrapper, returns the path unchanged.
+     *
+     * @param string $filePath
+     * @return string
+     */
+    protected function getFileRealPath($filePath)
+    {
+        if ($this->isSupportedStreamWrapper($filePath)) {
+            return $filePath;
+        }
+
+        // Need to use realpath to fix "Can't open file" on some Windows setup
+        return realpath($filePath);
+    }
+
+    /**
+     * Returns the scheme of the custom stream wrapper, if the path indicates a stream wrapper is used.
+     * For example, php://temp => php, s3://path/to/file => s3...
+     *
+     * @param string $filePath Path of the file to be read
+     * @return string|null The stream wrapper scheme or NULL if not a stream wrapper
+     */
+    protected function getStreamWrapperScheme($filePath)
+    {
+        $streamScheme = null;
+        if (preg_match('/^(\w+):\/\//', $filePath, $matches)) {
+            $streamScheme = $matches[1];
+        }
+        return $streamScheme;
+    }
+
+    /**
+     * Checks if the given path is an unsupported stream wrapper
+     * (like local path, php://temp, mystream://foo/bar...).
+     *
+     * @param string $filePath Path of the file to be read
+     * @return bool Whether the given path is an unsupported stream wrapper
+     */
+    protected function isStreamWrapper($filePath)
+    {
+        return ($this->getStreamWrapperScheme($filePath) !== null);
+    }
+
+    /**
+     * Checks if the given path is an supported stream wrapper
+     * (like php://temp, mystream://foo/bar...).
+     * If the given path is a local path, returns true.
+     *
+     * @param string $filePath Path of the file to be read
+     * @return bool Whether the given path is an supported stream wrapper
+     */
+    protected function isSupportedStreamWrapper($filePath)
+    {
+        $streamScheme = $this->getStreamWrapperScheme($filePath);
+        return ($streamScheme !== null) ?
+            in_array($streamScheme, $this->globalFunctionsHelper->stream_get_wrappers()) :
+            true;
+    }
+
     /**
      * Checks if a path is a PHP stream (like php://output, php://memory, ...)
      *
@@ -89,7 +160,8 @@ abstract class AbstractReader implements ReaderInterface
      */
     protected function isPhpStream($filePath)
     {
-        return (strpos($filePath, 'php://') === 0);
+        $streamScheme = $this->getStreamWrapperScheme($filePath);
+        return ($streamScheme === 'php');
     }
 
     /**
diff --git a/src/Spout/Reader/CSV/Reader.php b/src/Spout/Reader/CSV/Reader.php
index af02def..056d0a7 100644
--- a/src/Spout/Reader/CSV/Reader.php
+++ b/src/Spout/Reader/CSV/Reader.php
@@ -30,7 +30,7 @@ class Reader extends AbstractReader
     protected $encoding = EncodingHelper::ENCODING_UTF8;
 
     /** @var string Defines the End of line */
-    protected $endOfLineCharacter = "\n";    
+    protected $endOfLineCharacter = "\n";
 
     /**
      * Sets the field delimiter for the CSV.
@@ -82,7 +82,17 @@ class Reader extends AbstractReader
     {
         $this->endOfLineCharacter = $endOfLineCharacter;
         return $this;
-    }  
+    }
+
+    /**
+     * Returns whether stream wrappers are supported
+     *
+     * @return bool
+     */
+    protected function doesSupportStreamWrapper()
+    {
+        return true;
+    }
 
     /**
      * Opens the file at the given path to make it ready to be read.
diff --git a/src/Spout/Reader/ODS/Reader.php b/src/Spout/Reader/ODS/Reader.php
index c59ab57..b4093ae 100644
--- a/src/Spout/Reader/ODS/Reader.php
+++ b/src/Spout/Reader/ODS/Reader.php
@@ -19,6 +19,16 @@ class Reader extends AbstractReader
     /** @var SheetIterator To iterator over the ODS sheets */
     protected $sheetIterator;
 
+    /**
+     * Returns whether stream wrappers are supported
+     *
+     * @return bool
+     */
+    protected function doesSupportStreamWrapper()
+    {
+        return false;
+    }
+
     /**
      * Opens the file at the given file path to make it ready to be read.
      *
diff --git a/src/Spout/Reader/XLSX/Reader.php b/src/Spout/Reader/XLSX/Reader.php
index cf13517..42c6f02 100644
--- a/src/Spout/Reader/XLSX/Reader.php
+++ b/src/Spout/Reader/XLSX/Reader.php
@@ -37,6 +37,16 @@ class Reader extends AbstractReader
         return $this;
     }
 
+    /**
+     * Returns whether stream wrappers are supported
+     *
+     * @return bool
+     */
+    protected function doesSupportStreamWrapper()
+    {
+        return false;
+    }
+
     /**
      * Opens the file at the given file path to make it ready to be read.
      * It also parses the sharedStrings.xml file to get all the shared strings available in memory
diff --git a/tests/Spout/Reader/CSV/ReaderTest.php b/tests/Spout/Reader/CSV/ReaderTest.php
index c4c00ba..cdbca56 100644
--- a/tests/Spout/Reader/CSV/ReaderTest.php
+++ b/tests/Spout/Reader/CSV/ReaderTest.php
@@ -423,4 +423,50 @@ class ReaderTest extends \PHPUnit_Framework_TestCase
         $this->assertEquals($expectedRows, $allRows);
     }
 
+    /**
+     * @return void
+     */
+    public function testReadCustomStreamWrapper()
+    {
+        $allRows = [];
+        $resourcePath = 'spout://csv_standard';
+
+        // register stream wrapper
+        stream_wrapper_register('spout', SpoutTestStream::CLASS_NAME);
+
+        /** @var \Box\Spout\Reader\CSV\Reader $reader */
+        $reader = ReaderFactory::create(Type::CSV);
+        $reader->open($resourcePath);
+
+        foreach ($reader->getSheetIterator() as $sheet) {
+            foreach ($sheet->getRowIterator() as $row) {
+                $allRows[] = $row;
+            }
+        }
+
+        $reader->close();
+
+        $expectedRows = [
+            ['csv--11', 'csv--12', 'csv--13'],
+            ['csv--21', 'csv--22', 'csv--23'],
+            ['csv--31', 'csv--32', 'csv--33'],
+        ];
+        $this->assertEquals($expectedRows, $allRows);
+
+        // cleanup
+        stream_wrapper_unregister('spout');
+    }
+
+    /**
+     * @expectedException \Box\Spout\Common\Exception\IOException
+     *
+     * @return void
+     */
+    public function testReadWithUnsupportedCustomStreamWrapper()
+    {
+        /** @var \Box\Spout\Reader\CSV\Reader $reader */
+        $reader = ReaderFactory::create(Type::CSV);
+        $reader->open('unsupported://foobar');
+    }
+
 }
diff --git a/tests/Spout/Reader/CSV/SpoutTestStream.php b/tests/Spout/Reader/CSV/SpoutTestStream.php
new file mode 100644
index 0000000..fdaeb18
--- /dev/null
+++ b/tests/Spout/Reader/CSV/SpoutTestStream.php
@@ -0,0 +1,120 @@
+<?php
+
+namespace Box\Spout\Reader\CSV;
+
+/**
+ * Class SpoutTestStream
+ * Custom stream that reads CSV files located in the tests/resources/csv folder.
+ * For example: spout://foobar will point to tests/resources/csv/foobar.csv
+ *
+ * @package Box\Spout\Reader\CSV
+ */
+class SpoutTestStream
+{
+    const CLASS_NAME = __CLASS__;
+
+    const PATH_TO_CSV_RESOURCES = 'tests/resources/csv/';
+    const CSV_EXTENSION = '.csv';
+
+    /** @var int $position */
+    private $position;
+
+    /** @var resource $fileHandle */
+    private $fileHandle;
+
+    /**
+     * @param string $path
+     * @param int $flag
+     * @return array
+     */
+    public function url_stat($path, $flag)
+    {
+        $filePath = $this->getFilePathFromStreamPath($path);
+        return stat($filePath);
+    }
+
+    /**
+     * @param string $streamPath
+     * @return string
+     */
+    private function getFilePathFromStreamPath($streamPath)
+    {
+        $fileName = parse_url($streamPath, PHP_URL_HOST);
+        return self::PATH_TO_CSV_RESOURCES . $fileName . self::CSV_EXTENSION;
+    }
+
+    /**
+     * @param string $path
+     * @param string $mode
+     * @param int $options
+     * @param string $opened_path
+     * @return bool
+     */
+    public function stream_open($path, $mode, $options, &$opened_path)
+    {
+        $this->position = 0;
+
+        // the path is like "spout://csv_name" so the actual file name correspond the name of the host.
+        $filePath = $this->getFilePathFromStreamPath($path);
+        $this->fileHandle = fopen($filePath, $mode);
+
+        return true;
+    }
+
+    /**
+     * @param int $numBytes
+     * @return string
+     */
+    public function stream_read($numBytes)
+    {
+        $this->position += $numBytes;
+        return fread($this->fileHandle, $numBytes);
+    }
+
+    /**
+     * @return int
+     */
+    public function stream_tell()
+    {
+        return $this->position;
+    }
+
+    /**
+     * @param int $offset
+     * @param int|void $whence
+     * @return bool
+     */
+    public function stream_seek($offset, $whence = SEEK_SET)
+    {
+        $result = fseek($this->fileHandle, $offset, $whence);
+        if ($result === -1) {
+            return false;
+        }
+
+        if ($whence === SEEK_SET) {
+            $this->position = $offset;
+        } else if ($whence === SEEK_CUR) {
+            $this->position += $offset;
+        } else {
+            // not implemented
+        }
+
+        return true;
+    }
+
+    /**
+     * @return bool
+     */
+    public function stream_close()
+    {
+        return fclose($this->fileHandle);
+    }
+
+    /**
+     * @return bool
+     */
+    public function stream_eof()
+    {
+        return feof($this->fileHandle);
+    }
+}
diff --git a/tests/Spout/Reader/ODS/ReaderTest.php b/tests/Spout/Reader/ODS/ReaderTest.php
index df04ffc..8d9977b 100644
--- a/tests/Spout/Reader/ODS/ReaderTest.php
+++ b/tests/Spout/Reader/ODS/ReaderTest.php
@@ -363,6 +363,30 @@ class ReaderTest extends \PHPUnit_Framework_TestCase
         $this->assertEquals($expectedRows, $allRows);
     }
 
+    /**
+     * @expectedException \Box\Spout\Common\Exception\IOException
+     *
+     * @return void
+     */
+    public function testReadWithUnsupportedCustomStreamWrapper()
+    {
+        /** @var \Box\Spout\Reader\ODS\Reader $reader */
+        $reader = ReaderFactory::create(Type::ODS);
+        $reader->open('unsupported://foobar');
+    }
+
+    /**
+     * @expectedException \Box\Spout\Common\Exception\IOException
+     *
+     * @return void
+     */
+    public function testReadWithSupportedCustomStreamWrapper()
+    {
+        /** @var \Box\Spout\Reader\ODS\Reader $reader */
+        $reader = ReaderFactory::create(Type::ODS);
+        $reader->open('php://memory');
+    }
+
     /**
      * @param string $fileName
      * @return array All the read rows the given file
diff --git a/tests/Spout/Reader/XLSX/ReaderTest.php b/tests/Spout/Reader/XLSX/ReaderTest.php
index 2802d84..a3bdf7b 100644
--- a/tests/Spout/Reader/XLSX/ReaderTest.php
+++ b/tests/Spout/Reader/XLSX/ReaderTest.php
@@ -404,6 +404,30 @@ class ReaderTest extends \PHPUnit_Framework_TestCase
         $this->assertEquals($expectedRows, $allRows);
     }
 
+    /**
+     * @expectedException \Box\Spout\Common\Exception\IOException
+     *
+     * @return void
+     */
+    public function testReadWithUnsupportedCustomStreamWrapper()
+    {
+        /** @var \Box\Spout\Reader\XLSX\Reader $reader */
+        $reader = ReaderFactory::create(Type::XLSX);
+        $reader->open('unsupported://foobar');
+    }
+
+    /**
+     * @expectedException \Box\Spout\Common\Exception\IOException
+     *
+     * @return void
+     */
+    public function testReadWithSupportedCustomStreamWrapper()
+    {
+        /** @var \Box\Spout\Reader\XLSX\Reader $reader */
+        $reader = ReaderFactory::create(Type::XLSX);
+        $reader->open('php://memory');
+    }
+
     /**
      * @param string $fileName
      * @return array All the read rows the given file
diff --git a/tests/bootstrap.php b/tests/bootstrap.php
index ebe7689..902b4e9 100644
--- a/tests/bootstrap.php
+++ b/tests/bootstrap.php
@@ -3,6 +3,7 @@ require_once(dirname(__DIR__) . '/vendor/autoload.php');
 
 require_once(dirname(__DIR__) . '/tests/Spout/TestUsingResource.php');
 require_once(dirname(__DIR__) . '/tests/Spout/ReflectionHelper.php');
+require_once(dirname(__DIR__) . '/tests/Spout/Reader/CSV/SpoutTestStream.php');
 
 // Make sure a timezone is set to be able to work with dates
 date_default_timezone_set('UTC');